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Results of Urgent Thrombolysis in Pts with Major Stroke and Atherothrombotic Occlusion of Cervical Int Carotid Art
AJNR 19:1169-1175, Endo,S.,et al, 1998
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Article Abstract
Recanalization was accomplished in eight patients with intraarterial local thrombolysis;four of these patients had a good clinical outcome.Two factors characteristic of those whose treatment was successful were dramatic improvement of symptoms after partial recanalization achieved within 3 hours of onset and stabilized improvement after subsequent percutaneous transluminal angioplasty or carotid endarterectomy for residual atherosclerotic stenosis at the ICA origin.The results of this study suggest that urgent intraarterial local thrombolysis may be a successful treatment method for some patients in this critical clinical category if the treatment can be accomplished within 3 hours of ictus and followed by either angioplasty or endarterectomy for residual stenosis.
 
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carotid artery
carotid artery atherosclerosis
carotid artery disease
carotid artery occlusion,neck
cerebrovascular accident
cerebrovascular accident,acute management of
cerebrovascular accident,thrombolytic agents in treatment
endarterectomy,carotid
fibrinolytic agents
fibrinolytic agents,intra-arterial local infusion
internal carotid artery
prognosis
recanalization,arterial
transluminal angioplasty,carotid artery
treatment of neurologic disorder

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